Synthesis, Characterization, Antimicrobial and Time Killing Activities of New Sulfa-Derived Schiff Bases Coordinated with Cu(II)

Synthesis of three Schiff bases 5-bromo-3-nitro salicylaldehyde containing different sulfonamide group antibiotic compounds and their Cu(II) complexes was carried out. Structures all were characterized with spectroscopic methods, including Fourier transform infrared, proton nuclear magnetic resonance, elemental analysis. The in vitro antimicrobial activity ligands against Gram-negative Gram-positive bacteria the yeast Candida albicans evaluated. It determined that ligand showed outstanding almost microorganisms tested. has been observed newly synthesized have more effects than corresponding ligands. others (E. coli, L. monocytogenes, C. albicans), especially on Staphylococcus aureus Pseudomonas aeruginosa.